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Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol and metabolites found in Drosophila tissues.

The smallest p-values reveal tissues with the most significant changes in the pathway metabolites, between whole flies and individual tissues.

Tissue-Type Adult F/W p-value Adult M/W p-value Larvae/W p-value
Hemolymph 0.00003171130132650944 0.0001825075664305185 0.00000000000000000001954463944680236
Midgut 0.0000000000000000000008787480203152046 0.000000000000000000000000000004780341632670492 0.0000000000000000000005977861869109896
Tubules 0.000000000000000000003602855839241076 0.000000000000000000000000000000000000000000009708284124295333 0.00000000000000006501859831060448
Hindgut 0.0000000003883676143480801 0.0004967711973609169 0.00000000000000021224617233823776
Heart 0.0000000000005408118999194347 0.0004980320451503599 nm
VSpermatheca 0.0000017246754535553626 nm nm
Brain 0.0000000000000000005847439653890035 0.00000000013723279191339609 0.000000000000000024207458749384705
MSpermatheca 0.0000000001444978328787714 nm nm
Muscle 0.0000021658411786367246 0.004430516878569264 nm
Accessory Gland nm 0.000000000000039237184915060406 nm
Testes nm 0.00000000000009986053160376199 nm
VNC 0.00000000017606254389445977 0.000009097568011016446 nm
Trachea nm nm 0.0000000000000012209157435808908
Ovaries 0.0000000004732673599026678 nm nm
Crop 0.000000000019957019804028996 0.00000039274029368417097 nm
Rectal Pad 0.0000010347709875437578 0.000000021143711093658624 nm
Eye 0.000000000000000000000029578039226713394 0.0000000000006522351710308418 nm
Fat Body 0.00000000000001606094631845641 0.00000000000000000035800556349388 0.0000000000000000000022404693507655867
Carcass 0.00004259556155971171 0.9953245794517627 0.00000000012791988620833124
Salivary Gland 0.000021099559078134803 0.00000000572570431479189 0.00000000000000000018129991314039949
Head 0.00000000000024737310323243524 0.00000000000000000000000000000004285690365804499 nm


In this diagram the overrepresentation shown as ReactomeH highlights compounds (with associated peaks) that are found in FlyMet

Selected Pathway